Variant Review Workbench

Upload a VCF, choose the assembly, and generate a report with export files.

Runs use the shared ClinVar cache. Run files are removed after 24 hours.

New run Usage

Tool summary

Input: `.vcf` or `.vcf.gz`. Output: report preview plus HTML, JSON, and Markdown exports.

Input VCF

Accepts `.vcf` and `.vcf.gz` uploads up to 25 MB.

Pipeline Shared

Uses the same run pipeline and report outputs as the CLI.

Outputs 3 Formats

Open the report in the browser or download HTML, JSON, or Markdown.

Run Setup

Upload a file, select the assembly, and choose the output mode.

VCF upload

Use demo sample

Select a local `.vcf` or `.vcf.gz` file, or use the hosted demo sample.

Assembly Match the assembly to the VCF coordinates.

Options

Include PharmGKB enrichment Return export only

Variant limit Integer from 5 to 3000. Default: 3000.

Preferred export format Used only with export-only mode.

Data handling

Uploads are stored per run and removed by cleanup. Do not upload patient-identifying data.

Usage